Chimps \'r\' not us: 23 pairs chromosomes, not 24 (Introduction)

by David Turell @, Monday, May 30, 2016, 02:31 (2894 days ago) @ David Turell

Our chromosome pair 2 is supposedly fused and we therefore have 23 pairs, they have 24. The 'fusion' issue is all in dispute:-https://docs.google.com/document/d/1enllGchcY4Thz0xWFG8Rj8Y0bddOcBdIzKeoY1XxSqs/edit?pref=2&pli=1- First, the sequence was only about 800 bases long—not the 10,000 bases or more you would expect if two 5,000-base (or larger) telomeres fused together.-Second, the fusion-like sequence was very degenerate and only 70% similar to what one would expect of a pristine fusion sequence of the same size. Even if you assume an evolutionary timeline of up to six million years since the fusion event occurred, the data do not match up with known mutation rates or the variability found in human DNA. A third major problem is the fusion site contains no type of sequence called satellite DNA (satDNA). In chromosome fusion events that occur in nature in living mammals—a very rare event—the DNA signature always involves satDNA producing a DNA signature that occurs as either satDNA-satDNA or satDNA-teloDNA sequence.-***-Despite all of these serious difficulties, the greatest problem that evolutionists now have is the fact that the alleged fusion sequence is located in the middle of a functional gene.12 It is not a fossil remnant of a chromosomal accident at all but an important DNA regulatory feature called a promoter (genetic switch) inside a highly expressed gene.-***-But the evolutionary fusion story gets worse. The fusion-like sequence itself has an important functional purpose based on recent data available at the UCSC Genome Browser (genome.ucsc.edu) genomic database. Specifically, the fusion site sequence binds to at least 11 different transcription factors, including RNA polymerase II, the key enzyme that transcribes genes. Transcription factors are specialized proteins that turn genes off and on. The fact that these proteins specifically bind to the alleged fusion site sequence indicates that it is a promoter located inside the gene (Figure 2). It is common for human genes to have these promoter regions located both in front of the main body of the gene and inside them.-Comment: This is highly complex discussion, well beyond what I know. I had forgotten the discrepancy in pair number, and now the fusion theory is being questioned. If we and the apes have a common ancestor, how did this happen, before we branched off or after? Is it a God dabble? Even our chromosome number is different in kind.


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