Theoretical origin of life; never in water (Introduction)

by David Turell , Monday, October 02, 2017, 21:48 (2387 days ago) @ David Turell

Water destroys polymerization, so how did life start?

https://www.astrobio.net/news-exclusive/water-can-corrosive-life-alternative-solvents/

"Life on early Earth seems to have begun with a paradox: while life needs water as a solvent, the essential chemical backbones of early life-forming molecules fall apart in water. Our universal solvent, it turns out, can be extremely corrosive.

"Some have pointed to this paradox as a sign that life, or the precursor of life, originated elsewhere and was delivered here via comets or meteorites. Others have looked for solvents that could have the necessary qualities of water without that bond-breaking corrosiveness.

"In recent years the solvent often put forward as the eligible alternative to water is formamide, a clear and moderately irritating liquid consisting of hydrogen, carbon, nitrogen and oxygen. Unlike water, it does not break down the long-chain molecules needed to form the nucleic acids and proteins that make up life’s key initial instruction manual, RNA. Meanwhile it also converts via other useful reactions into key compounds needed to make nucleic acids in the first place.

"Although formamide is common in star-forming regions of space, scientists have struggled to find pathways for it to be prevalent, or even locally concentrated, on early Earth. In fact, it is hardly present on Earth today except as a synthetic chemical for companies.

"New research presented by Zachary Adam, an earth scientist at Harvard University, and Masashi Aono, a complex systems scientist at Earth-Life Science Institute (ELSI) at Tokyo Institute of Technology, has produced formamide by way of a surprising and reproducible pathway: bombardment with radioactive particles.

"The two and their colleagues exposed water and a mixture of two chemicals known to have existed on early Earth (hydrogen cyanide and aqueous acetonitrile) to the high-energy particles emitted from a cylinder of cobalt-60, an artificially produced radioactive isotope commonly used in cancer therapy. The result, they report, was the production of substantial amounts of formamide more quickly than earlier attempts by researchers using theoretical models and in laboratory settings.

"It remains unclear whether early Earth had enough radioactive material in the right places to produce the chemical reactions that led to the formation of formamide. And even if the conditions were right, scientists cannot yet conclude that formamide played an important role in the origin of life.

"Still, the new research furthers the evidence of the possible role of alternative solvents and presents a differing picture of the basis of life. Furthermore, it is suggestive of processes that might be at work on other exoplanets as well – where solvents other than water could, with energy supplied by radioactive sources, provide the necessary setting for simple compounds to be transformed into far more complex building blocks.

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"Adam and Aono remain agnostic about where the formamide-producing radioactive particles came from. But they are convinced that it is entirely possible that such reactions took place and helped produce an environment where each of the backbone precursors of RNA could readily be found in close quarters.

"Current scientific thinking about how formamide appeared on Earth focuses on limited arrival via asteroid impacts or through the concentration of the chemical in evaporated water-formamide mixtures in desert-like conditions. Adam acknowledges that the prevailing scientific consensus points to low amounts of formamide on early Earth.

“'We are not trying to argue to the contrary,” he said, “but we are trying to say that it may not matter.”

"If you have a unique place (or places) on the Earth creating significant amounts of formamide over a long period of time through radiolysis, then an opportunity exists for the onset of some unique chemistry that can support the production of essential precursor compounds for life, Adam said.

“'So, the argument then shifts to— how likely was it that this unique place existed? We only need one special location on the entire planet to meet these circumstances,” he said.
After that, the system set into motion would have the ability to bring together the chemical building blocks of life."

Comment: This study shows how difficult the origin of life is as a subject. Water is a major problem. Putting together all of the factors present in this study to start life doesn't tell us where the energy comes from for life to continue and spread from this one imaginary special spot. Chance can't work to start life, but that is what this study asks.